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PFKM Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89122912 Shop All Abnova Corporation Products
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400 μL
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89-122-912 400 μL
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Catalog No. 89-122-912 Supplier Abnova Corporation Supplier No. PAB2142
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PFKM.

The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. Mammalian PFK is a tetramer made up of various combinations of 3 subunits: muscle (PFKM), liver (PFKL; MIM 171860), and platelet (PFKP; MIM 171840), the genes for which are located on chromosomes 12q13, 21q22, and 10p, respectively. The composition of the tetramers differs according to the tissue type. Muscle and liver PFK are a homotetramers of 4M and 4L subunits, respectively. Erythrocytes contain both L and M subunits, which randomly tetramerize to form M4, L4, and M3L, M2L2, and ML3 hybrid forms of the holoenzyme (Vora et al., 1980 [PubMed 6444721]; Raben and Sherman, 1995 [PubMed 7550225]).[supplied by OMIM

Specifications

Antigen PFKM
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PFKM.
Dilution Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PFKM
Gene Alias GSD7/MGC8699/PFK-1/PFK-M/PFKX
Gene Symbols PFKM
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PFKM.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5213
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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