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MilliporeSigma™ Rabbit anti-phospho-Rac1/cdc42 (Ser71), Polyclonal,

Catalog No. 07896IMI Shop All MilliporeSigma Products
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Catalog No. 07-896-IMI Supplier MilliporeSigma™ Supplier No. 07896I
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Description

Rabbit Polyclonal Antibody

Specifically detects phospho-Rac1/cdc42 (Ser71) in Human samples, and it is validated for Immunoprecipitation, Western Blotting

Target of rapamycin complex 2 subunit MAPKAP1 (UniProt Q9BPZ7; also known as MEKK2-interacting protein 1, Mitogen-activated protein kinase 2-associated protein 1, mSIN1, Ras inhibitor MGC2745, SAPK-interacting protein 1, Stress-activated protein kinase-interacting 1, Stress-activated map kinase-interacting protein 1,, TORC2 subunit MAPKAP1) is encoded by the MAPKAP1 (also known as JC310, MIP1 SIN1, SIN1b, SIN1g) gene (Gene ID 79109) in human. mSIN1 is an essential component of the Torc2 complex. mTORC2 is comprised of mTOR, a large Ser/Thr protein kinase, along with mSIN1, GbL (mLST8), Protor1, Protor2, and Rictor. The mTORC2 complex is activated primarily downstream of PI3 Kinase and is known to affect cell proliferation and survival primarily by phosphorylating Akt on Ser473. Additionally, the mTORC2 complex is known to affect cytoskeletal organization and cell migration by exerting its effects through Rac, Rho, and PKC. mSIN1 is also known to directly interact with Ras, SPAKs, and JNK.
TRUSTED_SUSTAINABILITY

Specifications

Antigen phospho-Rac1/cdc42 (Ser71)
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Formulation Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. P63000
Gene Symbols RAC1; TC25; MIG5
Host Species Rabbit
Immunogen KLH-conjugated linear peptide corresponding to human phospho-Rac1/cdc42 (Ser71) near the N-Terminus.
Purification Method Affinity Purified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Signaling
Primary or Secondary Primary
Gene ID (Entrez) NP_008839
Target Species Human
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
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For Research Use Only

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