PIK3C2B, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PIK3C2B.

Supplier:  Abnova Corporation PAB3207

Catalog No. 89-130-888

Description

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq]

Specifications

• Antigen: PIK3C2B
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PIK3C2B.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: C2-PI3K/DKFZp686G16234
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5287
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry, Immunohistochemistry (Formalin/Paraffin), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50) The optimal working dilution should be determined by the end user.
• Gene: PIK3C2B
• Gene Symbols: PIK3C2B
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIK3C2B.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only