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PIK3C2B, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89130888 Shop All Abnova Corporation Products
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400 μL
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89-130-888 400 μL
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Catalog No. 89-130-888 Supplier Abnova Corporation Supplier No. PAB3207
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PIK3C2B.

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq]

Specifications

Antigen PIK3C2B
Applications Immunohistochemistry, Immunohistochemistry (Formalin/Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PIK3C2B.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PIK3C2B
Gene Alias C2-PI3K/DKFZp686G16234
Gene Symbols PIK3C2B
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIK3C2B.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5287
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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