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PKN1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89114093 Shop All Abnova Corporation Products
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89-114-093 50 μL
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Catalog No. 89-114-093 Supplier Abnova Corporation Supplier No. PAB0271
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PKN1.

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq

Sequence: EAPTLSPPRDARPLTAAEQ

Specifications

Antigen PKN1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PKN1.
Dilution The optimal working dilution should be determined by the end user.
Formulation In serum (0.05% sodium azide)
Gene PKN1
Gene Alias DBK/MGC46204/PAK1/PKN/PKN-ALPHA/PRK1/PRKCL1
Gene Symbols PKN1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids 921-929 of human PKN1.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5585
Target Species Canine, Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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