PLCG1 (phospho Y771), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-127-537	100 μg

Catalog No. 89-127-537 Supplier Abnova Corporation Supplier No. PAB25907

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PLCG1.

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: P-D-Yp-G-A

Specifications

• Antigen: PLCG1
• Applications: Immunofluorescence
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of PLCG1.
• Dilution: Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: PLCG1
• Gene Alias: PLC-II/PLC1/PLC148/PLCgamma1
• Gene Symbols: PLCG1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Y771 of human PLCG1.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5335
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only