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PLN Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89116801 Shop All Abnova Corporation Products
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89-116-801 100 μg
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Catalog No. 89-116-801 Supplier Abnova Corporation Supplier No. PAB13686
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Rabbit polyclonal antibody raised against synthetic peptide of PLN.

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]

Specifications

Antigen PLN
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PLN.
Dilution Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Gene PLN
Gene Alias CMD1P/PLB
Gene Symbols PLN
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids at N-terminus of human PLN.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5350
Test Specificity Identical to the related rat and mouse sequence.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG
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