POLG, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-025	400 μL

Catalog No. 89-130-025 Supplier Abnova Corporation Supplier No. PAB28515

Description

Rabbit polyclonal antibody raised against synthetic peptide of POLG

Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

• Antigen: POLG
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: polymerase (DNA directed), gamma
• Formulation: In PBS (0.09% sodium azide)
• Gene: POLG
• Gene Alias: FLJ27114, MDP1, PEO, POLG1, POLGA, SANDO, SCAE
• Gene Symbols: POLG
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 1120-1148 at C-terminal region at human POLG.
• Purification Method: Protein A purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5428
• Target Species: Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
• Form: Purified

For Research Use Only