Learn More
Description
This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | PRAME |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of PRAME. |
| Dilution | Western Blot (2 mg/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide) |
| Gene | PRAME |
| Gene Alias | MAPE/OIP4 |
| Gene Symbols | PRAME |
| Show More |
For Research Use Only
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.