MilliporeSigma™ Rabbit anti-PRDM1, Polyclonal,

Catalog No.	Quantity
ABE531MI	100 μL

Catalog No. ABE531MI Supplier MilliporeSigma™ Supplier No. ABE531

Description

Rabbit Polyclonal Antibody

Specifically detects PRDM1 in Human samples, and it is validated for Western Blotting

PR domain zinc finger protein 1 (also known as Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, PR domain-containing protein 1) is a transcriptional repressor encoded by the PRDM1 gene (or BLIMP1; Entrez Gene ID 639) in human. PRDM1/PLIMP1 protein silences target genes expression collaboratively with several chromatin-modifying enzymes as co-repressors, including histone deacetylases HDAC1/2, lysine methyltransferase G9a, protein arginine methyltransferase PRMT5, lysine-specific demethylase LSD1, as well as Groucho/Transducin-Like Enhancer of split (Gro/TLE) family of co-repressors. Prdm1/Blimp-1 contains an N-terminal PR/SET domain, a central proline- and serine-rich region, and 5 carboxy-terminal zinc fingers.

Specifications

• Antigen: PRDM1
• Applications: Western Blot
• Classification: Polyclonal
• Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: O75626
• Gene Symbols: PRDM1; BLIMP1
• Host Species: Rabbit
• Immunogen: His-tagged recombinant protein corresponding to human PRDM1.
• Purification Method: Affinity Purified
• Quantity: 100 μL
• Regulatory Status: RUO
• Research Discipline: Epigenetics and Nuclear Function
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_001189
• Target Species: Human
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only