PRKAA1 (phospho T172), Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKAA1.

Supplier:  Abnova Corporation PAB12602

Catalog No. 89-115-936

Description

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Sequence: LRTS

Specifications

• Antigen: PRKAA1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKAA1.
• Formulation: In TBS, pH 7.2 (BSA, 10% Proclin300)
• Gene Alias: AMPK/AMPKa1/MGC33776/MGC57364
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes PRKAA1 with a phosphorylated site of Thr 172. It does not cross-react with non-phosphospecific peptide.
• Content And Storage: Store at 4°C. For long term storage store at -20°C or -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: PRKAA1
• Gene Symbols: PRKAA1
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding T172 of human PRKAA1.
• Regulatory Status: RUO
• Gene ID (Entrez): 5562
• Target Species: Bovine, Canine, Chicken, Human, Insect, Mouse, Rat
• Form: Liquid

For Research Use Only