PRKCZ (phospho T410), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKCZ.
Manufacturer: Abnova Corporation PAB25884
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeqSequence: T-S-Tp-F-C
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKCZ.|
|In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|Synthetic phosphopeptide corresponding to residues surrounding T410 of human PRKCZ.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Human, Murine, Rat|
|Immunohistochemistry (PFA fixed)|
|Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.|
For Research Use Only