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PRKCZ (phospho T410), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKCZ.

Manufacturer:  Abnova Corporation PAB25884

Catalog No. 89-127-515


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Description

Description

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Sequence: T-S-Tp-F-C
Specifications

Specifications

PRKCZ
1 mg/mL
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKCZ.
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Liquid
PRKCZ
Synthetic phosphopeptide corresponding to residues surrounding T410 of human PRKCZ.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human, Murine, Rat
Immunohistochemistry (PFA fixed)
Unconjugated
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
PRKCZ
PKC-ZETA|PKC2
Rabbit
Affinity chromatography
RUO
Primary
5590
SDS
Documents
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