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PRKD3 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89131458 Shop All Abnova Corporation Products
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400 μL
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89-131-458 400 μL
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Catalog No. 89-131-458 Supplier Abnova Corporation Supplier No. PAB4545
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Rabbit polyclonal antibody raised against synthetic peptide of PRKD3.

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. [provided by RefSeq

Specifications

Antigen PRKD3
Applications Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PRKD3.
Dilution ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:50-100) Immunofluorescence (1:500) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PRKD3
Gene Alias EPK2/PKC-NU/PKD3/PRKCN/nPKC-NU
Gene Symbols PRKD3
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PRKD3.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23683
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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