PRNP (phospho S190), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-723	100 μL

Catalog No. 89-126-723 Supplier Abnova Corporation Supplier No. PAB25050

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRNP.

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20kb upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq

Specifications

• Antigen: PRNP
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRNP.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene: PRNP
• Gene Alias: ASCR/CD230/CJD/GSS/MGC26679/PRIP/PrP/PrP27-30/PrP33-35C/PrPc/prion
• Gene Symbols: PRNP
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S190 of PRNP.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5621
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only