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MilliporeSigma™ Rabbit anti-Pro-Decorin, Polyclonal,

Catalog No. ABT275MI Shop All MilliporeSigma Products
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ABT275MI 100 μL
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Description

Rabbit Polyclonal Antibody

Specifically detects Pro-Decorin in Human, Mouse samples, and it is validated for Immunohistochemistry

Decorin (UniProt P07585; also known as Bone proteoglycan II, PG40, PG-S2) is encoded by the DCN (also known as DSCD, DSPG2, PGII, PGS2, SLRR1B) gene (Entrez Gene ID 1634) in human. Decorin is a pericellular matrix proteoglycan structurally related to two other small proteoglycans, biglycan and fibromodulin. Decorin and biglycan are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while biglycan contains two chains. Decorin modulates collagen fibril formation as well as the bioactivity of various members of the transforming growth factor-beta (TGFbeta) superfamily. Decorin is initially translated as a preproprotein with an N-terminal signal peptide (aa1-16) and propeptide (aa17-30) sequence. Sequential removal of the signal peptide and the propeptide sequence produces pro- and mature decorin, respectively. (PMID 20026052).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pro-Decorin
Applications Immunohistochemistry
Classification Polyclonal
Formulation Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Accession No. P07585
Gene Symbols DCN; SLRR1B
Host Species Rabbit
Immunogen LPH-conjugated linear peptide corresponding to the signal and propeptide of human Pro-Decorin.
Purification Method Unpurified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Cell Structure
Primary or Secondary Primary
Gene ID (Entrez) NP_001911
Target Species Human, Mouse
Content And Storage Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Form Serum
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For Research Use Only

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