MilliporeSigma™ Rabbit anti-Proline-rich Protein 14, Polyclonal,

Catalog No.	Quantity
ABE1398MI	100 μL

Catalog No. ABE1398MI Supplier MilliporeSigma™ Supplier No. ABE1398

Description

Rabbit Polyclonal Antibody

Specifically detects Proline-rich Protein 14 in Human, Mouse, Rat samples, and it is validated for Western Blotting

Proline-rich protein 14 (UniProt Q9BWN1) is encoded by the PRR14 gene in human (Gene ID 78994). Proline-rich protein 14 participates in the tethering of heterochromatin to the inner nuclear periphery by associating with the nuclear lamina and attaching to heterochromatin through its binding partner, heterochromatin protein 1 (HP1). After disassembly early in mitosis, Proline-rich protein 14 reassembles via binding to anaphase chromosomes through HP1, then via association with the nuclear lamina in telophase. PRR14 may thereby play a role in specifying HP1-bound heterochromatin for reattachment to the nuclear lamina at mitotic exit.

Specifications

• Antigen: Proline-rich Protein 14
• Applications: Western Blot
• Classification: Polyclonal
• Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: Q9BWN1
• Gene Symbols: PRR14
• Host Species: Rabbit
• Immunogen: KLH-conjugated linear peptide corresponding to human Proline-rich Protein 14.
• Purification Method: Affinity Purified
• Quantity: 100 μL
• Regulatory Status: RUO
• Research Discipline: Epigenetics and Nuclear Function
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_076936
• Target Species: Human, Mouse, Rat
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only