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PSENEN (KLH), Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89113974 Shop All Abnova Corporation Products
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89-113-974 100 μg
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Catalog No. 89-113-974 Supplier Abnova Corporation Supplier No. PAB0141

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Rabbit polyclonal antibody raised against synthetic peptide conjugated to KLH.

Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq]

Specifications

Antigen PSENEN (KLH)
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide conjugated to KLH.
Dilution Western Blot (5-10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from purified antibody
Gene PSENEN
Gene Alias MDS033/MSTP064/PEN-2/PEN2
Gene Symbols PSENEN
Host Species Rabbit
Immunogen A synthetic peptide (conjugated to KLH) corresponding to N-terminus 11 amino acids of human PSENEN.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55851
Target Species Hamster, Human, Mouse
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with sterile water store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
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