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PTGS1 Rabbit anti-Bovine, Dog, Human, Sheep, Polyclonal Antibody, Abnova™

Catalog No. 89116773 Shop All Abnova Corporation Products
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89-116-773 1 mL
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Catalog No. 89-116-773 Supplier Abnova Corporation Supplier No. PAB13623
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Description

Rabbit polyclonal antibody raised against PTGS1.

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq

Specifications

Antigen PTGS1
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against PTGS1.
Dilution ELISA (1:1000) Western Blot (1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene PTGS1
Gene Alias COX1/COX3/PCOX1/PGG/HS/PGHS-1/PGHS1/PHS1/PTGHS
Gene Symbols PTGS1
Host Species Rabbit
Immunogen Sheep PTGS1.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5742
Test Specificity This antibody is reactive in most mammalian species including, human, ovine, bovine, and canine, weakly with mouse and rat. Detects COX-1 expression for human and sheep while reacting weakly with Cyclooxygenase 2 (COX-2).
Target Species Bovine, Canine, Human, Sheep
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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