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PTK2B Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PTK2B.

Manufacturer:  Abnova Corporation PAB18132

Catalog No. 89-119-705


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Description

Description

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq

Specifications

Specifications

PTK2B
1 mg/mL
Rabbit polyclonal antibody raised against synthetic peptide of PTK2B.
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Liquid
PTK2B
A synthetic peptide corresponding to human PTK2B.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
This antibody is specific to PTK2B.
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
PTK2B
CADTK|CAKB|FADK2|FAK2|FRNK|PKB|PTK|PYK2|RAFTK
Rabbit
Affinity purification
RUO
Primary
2185
Human, Murine, Rat
SDS
Documents
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