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Description
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq
Specifications
Specifications
| Antigen | PTP4A1 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against full length recombinant PTP4A1. |
| Dilution | ELISA (1:1000) Western Blot (1:100-500) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | PTP4A1 |
| Gene Alias | DKFZp779M0721/HH72/PRL-1/PRL1/PTP(CAAX1)/PTPCAAX1 |
| Gene Symbols | PTP4A1 |
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