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PTPN11 (phospho Y580), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PTPN11.
Supplier: Abnova Corporation PAB25889
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq
Sequence: R-V-Yp-E-NSpecifications
PTPN11 | |
Polyclonal | |
Unconjugated | |
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user. | |
PTPN11 | |
PTPN11 | |
Synthetic phosphopeptide corresponding to residues surrounding Y580 of human PTPN11. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Liquid |
Immunohistochemistry (PFA fixed) | |
1 mg/mL | |
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PTPN11. | |
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) | |
BPTP3/CFC/MGC14433/NS1/PTP-1D/PTP2C/SH-PTP2/SH-PTP3/SHP2 | |
Rabbit | |
Affinity chromatography | |
RUO | |
5781 | |
Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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