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PTPN11 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PTPN11.

Supplier:  Abnova Corporation PAB26820

Catalog No. 89-128-464


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Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq

Sequence: H-E-Yp-T-N
Specifications

Specifications

PTPN11
Polyclonal
Unconjugated
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
PTPN11
PTPN11
A synthetic peptide corresponding to residues surrounding Y542 of human PTPN11.
100 μg
Primary
Human, Mouse, Rat
Liquid
Immunohistochemistry (PFA fixed), Western Blot
1 mg/mL
Rabbit polyclonal antibody raised against synthetic peptide of PTPN11.
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
BPTP3/CFC/MGC14433/NS1/PTP-1D/PTP2C/SH-PTP2/SH-PTP3/SHP2
Rabbit
Affinity chromatography
RUO
5781
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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