PTPN11 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of PTPN11.
Supplier: Abnova Corporation PAB26820
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeqSequence: H-E-Yp-T-N
|Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
|A synthetic peptide corresponding to residues surrounding Y542 of human PTPN11.
|Human, Mouse, Rat
|Immunohistochemistry (PFA fixed), Western Blot
|Rabbit polyclonal antibody raised against synthetic peptide of PTPN11.
|In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only