PTPN21, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-131-272	400 μL

Catalog No. 89-131-272 Supplier Abnova Corporation Supplier No. PAB4102

Description

Rabbit polyclonal antibody raised against synthetic peptide of PTPN21.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq

Specifications

• Antigen: PTPN21
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PTPN21.
• Dilution: ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: PTPN21
• Gene Alias: PTPD1/PTPRL10
• Gene Symbols: PTPN21
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human PTPN21.
• Purification Method: Protein G purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11099
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only