PTPN6 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of PTPN6.
Manufacturer: Abnova Corporation PAB18105
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of PTPN6.|
|In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|A synthetic peptide corresponding to human PTPN6.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody is specific to PTPN6.|
|ELISA, Immunohistochemistry (PFA fixed), Western Blot|
|Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.|
|Human, Murine, Rat|
For Research Use Only