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PTPN6 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PTPN6.

Manufacturer:  Abnova Corporation PAB18105

Catalog No. 89-119-678


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Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq

Specifications

Specifications

PTPN6
1 mg/mL
Rabbit polyclonal antibody raised against synthetic peptide of PTPN6.
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Liquid
PTPN6
A synthetic peptide corresponding to human PTPN6.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
This antibody is specific to PTPN6.
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
PTPN6
HCP|HCPH|HPTP1C|PTP-1C|SH-PTP1|SHP-1|SHP-1L|SHP1
Rabbit
Affinity purification
RUO
Primary
5777
Human, Murine, Rat
SDS
Documents
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