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PTPRE Rabbit anti-Bats, Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89129845 Shop All Abnova Corporation Products
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50 μg
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89-129-845 50 μg
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Catalog No. 89-129-845 Supplier Abnova Corporation Supplier No. PAB28343
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Description

Rabbit polyconal antibody raised against synthetic peptide of PTPRE.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq]

Specifications

Antigen PTPRE
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyconal antibody raised against synthetic peptide of PTPRE.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 ug/ml) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PTPRE
Gene Alias DKFZp313F1310/FLJ57799/FLJ58245/HPTPE/PTPE/R-PTP-EPSILON
Gene Symbols PTPRE
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 18 amino acids at cytoplasmic domain of human PTPRE.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5791
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTPRA (67%).
Target Species Bat, Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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