PTPRM Rabbit anti-Bovine, Dog, Human, Monkey, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PTPRM.

Supplier:  Abnova Corporation PAB16289

Catalog No. 89-118-163

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq

Specifications

• Antigen: PTPRM
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PTPRM.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: MGC166994/PTPRL1/R-PTP-MU/RPTPM/RPTPU/hR-PTPu
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5797
• Target Species: Bovine, Canine, Human, Monkey, Rabbit
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: PTPRM
• Gene Symbols: PTPRM
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human PTPRM.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: Internal domain of human.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only