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PTPRM Rabbit anti-Bovine, Dog, Human, Monkey, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89118163 Shop All Abnova Corporation Products
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89-118-163 50 μg
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Catalog No. 89-118-163 Supplier Abnova Corporation Supplier No. PAB16289
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PTPRM.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq

Specifications

Antigen PTPRM
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PTPRM.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PTPRM
Gene Alias MGC166994/PTPRL1/R-PTP-MU/RPTPM/RPTPU/hR-PTPu
Gene Symbols PTPRM
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human PTPRM.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5797
Test Specificity Internal domain of human.
Target Species Bovine, Canine, Human, Monkey, Rabbit
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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