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Description
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq
Specifications
Specifications
| Antigen | purified 6-His mPGES-1 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against recombinant purified 6-His mPGES-1. |
| Dilution | Western Blot (1:10000) Immunohistochemistry (Frozen sections) (1:6000) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from serum |
| Gene | PTGES |
| Gene Alias | MGC10317/MGST-IV/MGST1-L1/MGST1L1/MPGES/PGES/PIG12/PP102/PP1294/TP53I12/mPGES-1 |
| Gene Symbols | PTGES |
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