RAD50, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-561	100 μL

Catalog No. 89-115-561 Supplier Abnova Corporation Supplier No. PAB12052

Description

Rabbit polyclonal antibody raised against partial recombinant RAD50.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq

Specifications

• Antigen: RAD50
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against partial recombinant RAD50.
• Dilution: Western Blot (1:1000-1:10000) Immunoprecipitation (1-5 ug/mL lysate) The optimal working dilution should be determined by the end user.
• Formulation: No additive
• Gene: RAD50
• Gene Alias: RAD50-2/hRad50
• Gene Symbols: RAD50
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to amino acids 628-787 of human RAD50.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10111
• Test Specificity: This antibody is specific to human Rad50.
• Target Species: Human
• Content And Storage: Store at 4°C for short term. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only