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RAD51 Rabbit anti-Chicken, Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89115420 Shop All Abnova Corporation Products
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89-115-420 50 μL
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Catalog No. 89-115-420 Supplier Abnova Corporation Supplier No. PAB1184
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Description

Rabbit polyclonal antibody raised against full-length recombinant RAD51.

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen RAD51
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against full length recombinant RAD51.
Dilution Western Blot (1:2000-1:10000) The optimal working dilution should be determined by the end user.
Formulation In buffer containing 0.09% sodium azide
Gene RAD51
Gene Alias BRCC5/HRAD51/HsRad51/HsT16930/RAD51A/RECA
Gene Symbols RAD51
Host Species Rabbit
Immunogen Recombinant protein corresponding to full length human RAD51.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5888
Target Species Chicken, Human, Mouse
Content And Storage Store the kit at -20°C.
Form Liquid
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For Research Use Only

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