RAD51 (phospho T310), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic phosphopeptide of RAD51.
Manufacturer: Abnova Corporation PAB15924
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
|ELISA (1:2000-1:5000) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|ELISA, Western Blot|
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of RAD51.|
|In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)|
|Synthetic phosphopeptide corresponding to residues surrounding T310 of human RAD51.|
For Research Use Only