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Description
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq
Specifications
Specifications
| Antigen | RAPGEF1 |
| Applications | ELISA, Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of RAPGEF1. |
| Dilution | Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gene | RAPGEF1 |
| Gene Alias | C3G/DKFZp781P1719/GRF2 |
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