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RB1 (phospho S780), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.

Supplier:  Abnova Corporation PAB25409

Catalog No. 89-127-035


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Description

Description

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq

Sequence: T-L-Sp-P-I
Specifications

Specifications

RB1
Polyclonal
Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
OSRC/RB/p105-Rb/pRb/pp110
Rabbit
Affinity purification
RUO
5925
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
RB1
RB1
Synthetic phosphopeptide corresponding to residues surrounding S780 of human RB1.
100 μg
Primary
Human, Mouse, Rat
Liquid
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