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RB1 (phospho S780), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.
Supplier: Abnova Corporation PAB25409
Description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq
Sequence: T-L-Sp-P-ISpecifications
RB1 | |
Polyclonal | |
Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1. | |
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) | |
OSRC/RB/p105-Rb/pRb/pp110 | |
Rabbit | |
Affinity purification | |
RUO | |
5925 | |
Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Immunohistochemistry (PFA fixed), Western Blot | |
Unconjugated | |
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. | |
RB1 | |
RB1 | |
Synthetic phosphopeptide corresponding to residues surrounding S780 of human RB1. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Liquid |
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