RB1 (phospho S807), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-127-034	100 μg

Catalog No. 89-127-034 Supplier Abnova Corporation Supplier No. PAB25408

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq

Sequence: Y-I-Sp-P-L

Specifications

• Antigen: RB1
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: RB1
• Gene Alias: OSRC/RB/p105-Rb/pRb/pp110
• Gene Symbols: RB1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S807 of human RB1.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5925
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only