RGR Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of RGR.

Supplier:  Abnova Corporation PAB26527

Catalog No. 89-128-167

Description

This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: RGR
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of RGR.
• Formulation: In PBS (0.09% sodium azide)
• Gene Symbols: RGR
• Immunogen: A synthetic peptide corresponding to 16 amino acids at 1st extracellular domain of human RGR.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SSTR1 (50%).
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: RGR
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5995
• Target Species: Human, Monkey
• Form: Liquid

For Research Use Only