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RGR Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89128169 Shop All Abnova Corporation Products
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89-128-169 50 μg
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Catalog No. 89-128-169 Supplier Abnova Corporation Supplier No. PAB26529
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Description

Rabbit polyclonal antibody raised against synthetic peptide of RGR.

This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Antigen RGR
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of RGR.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10-19 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene RGR
Gene Symbols RGR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acids at 3rd cytoplasmic domain of human RGR.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5995
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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