RNASEH2A, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-118-519	100 μg

Catalog No. 89-118-519 Supplier Abnova Corporation Supplier No. PAB16685

Description

Rabbit polyclonal antibody raised against synthetic peptide of RNASEH2A.

The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid

Specifications

• Antigen: RNASEH2A
• Applications: ELISA, Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of RNASEH2A.
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: RNASEH2A
• Gene Alias: AGS4/JUNB/RNASEHI/RNHIA/RNHL
• Gene Symbols: RNASEH2A
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to internal region 17 amino acids of human RNASEH2A.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10535
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only