ROCK1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-967	100 μg

Catalog No. 89-120-967 Supplier Abnova Corporation Supplier No. PAB19432

Description

Rabbit polyclonal antibody raised against synthetic peptide of ROCK1.

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq

Specifications

• Antigen: ROCK1
• Applications: ELISA, Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ROCK1.
• Dilution: Western Blot (1 ug/mL) Immunocytochemistry (10 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: ROCK1
• Gene Alias: MGC131603/MGC43611/P160ROCK/PRO0435
• Gene Symbols: ROCK1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 15 amino acids near N-terminus of human ROCK1.
• Purification Method: Peptide affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6093
• Test Specificity: ROCK1 antibody is predicted to not cross-react with other ROCK protein family members.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only