RPS6KB1 (phospho T421), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-128-423	100 μg

Catalog No. 89-128-423 Supplier Abnova Corporation Supplier No. PAB26781

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of RPS6KB1.

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq

Sequence: P-R-Tp-P-V

Specifications

• Antigen: RPS6KB1
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of RPS6KB1.
• Dilution: Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: RPS6KB1
• Gene Alias: PS6K/S6K/S6K1/STK14A/p70(S6K)-alpha/p70-S6K/p70-alpha
• Gene Symbols: RPS6KB1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding T421 of human RPS6KB1.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6198
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only