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RRM1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89117292 Shop All Abnova Corporation Products
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89-117-292 100 μL
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Catalog No. 89-117-292 Supplier Abnova Corporation Supplier No. PAB14831

Description

Rabbit polyclonal antibody raised against synthetic peptide of RRM1.

This gene encodes one of two nonidentical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq

Specifications

Antigen RRM1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of RRM1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene RRM1
Gene Alias R1/RIR1/RR1
Gene Symbols RRM1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human RRM1.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6240
Test Specificity Epitope: C-terminus.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
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For Research Use Only

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