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Description
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM
Specifications
Specifications
| Antigen | S1PR5 |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of S1PR5. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-7 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | S1PR5 |
| Gene Alias | EDG8/Edg-8/S1P5/SPPR-1/SPPR-2 |
| Gene Symbols | S1PR5 |
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