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Description
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq
Specifications
Specifications
| Antigen | SIGLEC1 |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Monoclonal |
| Clone | SP213 |
| Conjugate | Unconjugated |
| Description | Rabbit monoclonal antibody raised against synthetic peptide of SIGLEC1. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide) |
| Gene | SIGLEC1 |
| Gene Alias | CD169/DKFZp667F058/FLJ00051/FLJ00055/FLJ00073/FLJ00411/FLJ32150/SIGLEC-1/SN/dJ1009E24.1 |
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