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SIRPA, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89117089 Shop All Abnova Corporation Products
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100 μg
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89-117-089 100 μg
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Catalog No. 89-117-089 Supplier Abnova Corporation Supplier No. PAB14459
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Description

Rabbit polyclonal antibody raised against synthetic peptide of SIRPA.

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq

Specifications

Antigen SIRPA
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of SIRPA.
Dilution Western Blot (1:1000-1:2000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (0.02% sodium azide)
Gene SIRPA
Gene Alias BIT/CD172A/MFR/MYD-1/P84/PTPNS1/SHPS-1/SHPS1/SIRP/SIRP-ALPHA-1/SIRPalpha/SIRPalpha2
Gene Symbols SIRPA
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human SIRPA.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140885
Target Species Bovine, Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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