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SNCA Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115401 Shop All Abnova Corporation Products
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89-115-401 100 μL
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Catalog No. 89-115-401 Supplier Abnova Corporation Supplier No. PAB11817

Description

Rabbit polyclonal antibody raised against synthetic peptide of SNCA.

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq]

Specifications

Antigen SNCA
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of SNCA.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene SNCA
Gene Alias MGC110988/NACP/PARK1/PARK4/PD1
Gene Symbols SNCA
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human SNCA.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6622
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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