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SOCS1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Shop All Abnova Corporation ProductsDescription
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq
Specifications
Specifications
| Antigen | SOCS1 |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic protein of SOCS1. |
| Dilution | ELISA (1-2 ug/mL) Western Blot (2-10 ug/mL) Immunohistochemistry (2-10 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from PBS. |
| Gene | SOCS1 |
| Gene Alias | CIS1/CISH1/JAB/SOCS-1/SSI-1/SSI1/TIP3 |
| Gene Symbols | SOCS1 |
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For Research Use Only
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