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SOCS1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89121095 Shop All Abnova Corporation Products
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89-121-095 100 μg
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Catalog No. 89-121-095 Supplier Abnova Corporation Supplier No. PAB19568
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Rabbit polyclonal antibody raised against synthetic protein of SOCS1.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq

Specifications

Antigen SOCS1
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic protein of SOCS1.
Dilution ELISA (1-2 ug/mL) Western Blot (2-10 ug/mL) Immunohistochemistry (2-10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from PBS.
Gene SOCS1
Gene Alias CIS1/CISH1/JAB/SOCS-1/SSI-1/SSI1/TIP3
Gene Symbols SOCS1
Host Species Rabbit
Immunogen Synthetic protein corresponding to human SOCS1.
Purification Method Protein G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8651
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
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