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SOCS2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115443 Shop All Abnova Corporation Products
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89-115-443 100 μL
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Catalog No. 89-115-443 Supplier Abnova Corporation Supplier No. PAB11892

Description

Rabbit polyclonal antibody raised against synthetic peptide of SOCS2.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq

Specifications

Antigen SOCS2
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of SOCS2.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene SOCS2
Gene Alias CIS2/Cish2/SOCS-2/SSI-2/SSI2/STATI2
Gene Symbols SOCS2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human SOCS2.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8835
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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