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SORT1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89114381 Shop All Abnova Corporation Products
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89-114-381 100 μL
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Catalog No. 89-114-381 Supplier Abnova Corporation Supplier No. PAB0734
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Rabbit polyclonal antibody raised against partial recombinant SORT1.

This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq

Specifications

Antigen SORT1
Applications ELISA, Immunohistochemistry (Frozen)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against partial recombinant SORT1.
Dilution Immunohistochemistry (1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from PBS
Gene SORT1
Gene Alias Gp95/NT3
Gene Symbols SORT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to extracellular region of human SORT1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6272
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
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