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SPHK1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89117642 Shop All Abnova Corporation Products
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89-117-642 100 μL
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Catalog No. 89-117-642 Supplier Abnova Corporation Supplier No. PAB15559
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Description

Rabbit polyclonal antibody raised against SPHK1.

Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM

Specifications

Antigen SPHK1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against SPHK1.
Dilution Immunoprecipitation (5-15 ug/mg lysate) Western Blot (1:2000-1:10000) The optimal working dilution should be determined by the end user.
Formulation In Tris-citrate/phosphate, pH 7-8 (0.09% sodium azide)
Gene SPHK1
Gene Alias SPHK
Gene Symbols SPHK1
Host Species Rabbit
Immunogen Amino acids 334-384 of human SPHK1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8877
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
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For Research Use Only

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