SPHK1 Rabbit anti-Human, Monkey, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of SPHK1.

Supplier:  Abnova Corporation PAB2801

Catalog No. 89-129-525

Description

Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM

Specifications

• Antigen: SPHK1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of SPHK1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: SPHK
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 8877
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: SPHK1
• Gene Symbols: SPHK1
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human SPHK1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Mouse, Rat
• Form: Liquid

For Research Use Only