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SPHK1 Rabbit anti-Human, Monkey, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89129525 Shop All Abnova Corporation Products
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400 μL
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Catalog No. Quantity
89-129-525 400 μL
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Catalog No. 89-129-525 Supplier Abnova Corporation Supplier No. PAB2801

Description

Rabbit polyclonal antibody raised against synthetic peptide of SPHK1.

Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM

Specifications

Antigen SPHK1
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of SPHK1.
Dilution Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene SPHK1
Gene Alias SPHK
Gene Symbols SPHK1
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to internal region of human SPHK1.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8877
Target Species Human, Monkey, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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