SPTLC1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-928	100 μg

Catalog No. 89-120-928 Supplier Abnova Corporation Supplier No. PAB19392

Description

Rabbit polyclonal antibody raised against synthetic peptide of SPTLC1.

Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq]

Specifications

• Antigen: SPTLC1
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of SPTLC1.
• Dilution: Western Blot (1 ug/mL) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: SPTLC1
• Gene Alias: HSAN/HSAN1/HSN1/LBC1/LCB1/MGC14645/SPT1/SPTI
• Gene Symbols: SPTLC1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 17 amino acids near C-terminus of human SPTLC1.
• Purification Method: Peptide affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10558
• Test Specificity: At least two isoforms of SPTLC1 are known to exist; this antibody will detect only isoform a. This antibody is predicted to not cross-react with SPT2.
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only