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SQSTM1 Rabbit anti-Bovine, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89117007 Shop All Abnova Corporation Products
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89-117-007 100 μL
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Catalog No. 89-117-007 Supplier Abnova Corporation Supplier No. PAB14333
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Rabbit polyclonal antibody raised against synthetic peptide of SQSTM1.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NFkb in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq

Sequence: IGAALDTIQYSKH

Specifications

Antigen SQSTM1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of SQSTM1.
Dilution Immunohistochemistry (1:500-1:5000) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from PBS
Gene SQSTM1
Gene Alias A170/OSIL/PDB3/ZIP3/p60/p62/p62B
Gene Symbols SQSTM1
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with blue carrier protein) corresponding to amino acids 424-436 of human SQSTM1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8878
Test Specificity The specificity was confirmed by immunohistochemical analysis on paraffin embedded human brain.
Target Species Bovine, Human, Mouse, Rat
Content And Storage Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
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