SQSTM1 Rabbit anti-Bovine, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of SQSTM1.

Supplier:  Abnova Corporation PAB14333

Catalog No. 89-117-007

Description

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NFkb in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq

Sequence: IGAALDTIQYSKH

Specifications

• Antigen: SQSTM1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of SQSTM1.
• Formulation: Lyophilized from PBS
• Gene Alias: A170/OSIL/PDB3/ZIP3/p60/p62/p62B
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: The specificity was confirmed by immunohistochemical analysis on paraffin embedded human brain.
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:500-1:5000) The optimal working dilution should be determined by the end user.
• Gene: SQSTM1
• Gene Symbols: SQSTM1
• Immunogen: A synthetic peptide (conjugated with blue carrier protein) corresponding to amino acids 424-436 of human SQSTM1.
• Regulatory Status: RUO
• Gene ID (Entrez): 8878
• Target Species: Bovine, Human, Mouse, Rat
• Form: Lyophilized

For Research Use Only