SREBF1 Rabbit anti-Mouse, Pig, Rat, DyLight 488, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-117-496	100 μL

Catalog No. 89-117-496 Supplier Abnova Corporation Supplier No. PAB15201

Description

Rabbit polyclonal antibody raised against synthetic peptide of SREBF1.

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: SREBF1
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: DyLight 488
• Description: Rabbit polyclonal antibody raised against synthetic peptide of SREBF1.
• Dilution: Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 50mM sodium borate
• Gene: SREBF1
• Gene Alias: SREBP-1c/SREBP1/bHLHd1
• Gene Symbols: SREBF1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids 300-400 of human SREBF1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6720
• Test Specificity: This is specific to SREBP1. By Western blot a band is seen at ∼65KDa.
• Target Species: Mouse, Pig, Rat
• Content And Storage: Store at 4°C. Do not freeze.
• Form: Liquid

For Research Use Only